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- Ayuda todas las células del organismo a funcionar a su nivel óptimo de energía.
- Contribuye a reducir los niveles de triglicéridos en la sangre.
- Interviene en la prevención de ciertas enfermedades cardiovasculares, especialmente de la arritmia cardiaca.
- Ayuda a perder peso cuando el suplemento se combina con un régimen pobre en glúcidos.
- Aumenta de forma natural el nivel de energía.
- Mejora de forma significativa los resultados de los deportistas de fondo y reduce el estrés muscular provocado por el ejercicio.
El ALC mejora las capacidades cognitivas de los seres humanos que gozan de buena salud (atención, coordinación visual, reflejos, velocidad de ejecución de las tareas intelectuales) (Lino et al, 1992).
El ALC mejora las funciones cognitivas, estado emocional, y comportamiento social de los pacientes víctimas de deficiencia memorial asociada al envejecimiento (Cipollo y Chiari, 1990. Las mejorías persisten mucho tiempo después de dejar la suplementación (Vecchi y al, 1991).
El ALC reduce los síntomas de la depresión y mejora la percepción de la calidad de vida (Bella et al, 1990) (Garzva et al, 1990).
El ALC retarda el deterioro cognitivo en pacientes víctimas de la enfermedad de Alzheimer (dicho estudio utilizó una dosis de 2,5 gr/día durante 3 meses (Sano et al, 1992) y el resultado fue confirmado por otros estudios.
El ALC mejora los síntomas de la senilidad (Bonavita, 1986) (Cucinotta et al, 1988). 2 gramos de ALC/día mejoran el comportamiento, los tests memoriales, la atención y la verbalización (Universidad de Parma, Passeri et al, 1990). El ALC mejora la circulación cerebral en pacientes víctimas de insuficiencia cerebro-vascular (Postiglione et al, 1990) (Rosadini et al, 1988).
El ALC reduce la formación de lipofuscine (el “detritus” celular que forma “las manchas de envejecimiento”) y disminuye los depósitos existentes de lipofuscine (Komsomol, 1988) (Amenta et Al, 1989).
Los deportistas, los vegetarianos y las personas en situación de sobrepeso deberían optar por el suplemento de L-Carnitina en vez del Acetyl-L-Carnitina, más costoso y más “cerebroactivo”, o bien combinar ambos suplementos. El nutricionista americano Robert Crayon, autor de un libro sobre este súper nutriente recomienda combinar L-Carnitina con Acetyl-l-Carnitina en partes iguales.
Recomiendo el tartrato de l-Carnitina, es una forma patentada, especialmente estable y no higroscópica de l-Carnitina.
Alpha lipoic acid (ALA) and Acetyl-L-Carnitine (ALCAR) are two nutrients that have been the subject of considerable research as of late. Both compounds display many impressive properties, and have many synergistic effects when combined. The ALA and ALCAR combination has significant anti-aging and cognition improving properties and can also be effectively used for fat loss and to increase athletic performance.
ALCAR is the acetylated version of L-carnitine, an important amino acid that improves mitochondrial function and plays a role in fatty acid oxidation. ALCAR may be more bioavailable than l-carnitine, and also provides acetyl groups for synthesis of compounds such as acetylcholine. ALCAR also has a cholinomimetic effect on its own. Both ALCAR and l-carnitine have been successfully used to treat a very wide range of conditions with little or no side effects.
ALA is a naturally occuring antioxidant enzyme that is also an important mitochondrial component. It has many properties that make it superior to most other antioxidants. Like ALCAR, ALA has been used to treat various conditions, particularly diabetes.
Studies with both ALCAR and L-carnitine indicate that they can improve athletic performance. This is because carnitine improves fatty acid oxidation, increasing fuel availability and preserving muscle glycogen. Carnitine also appears to favorably effect markers of recovery and the hormonal response to resistance exercise. Many trials have found that supplemental carnitine improves exercise performance in individuals that are impaired in some way, such as patients with angina, patients with cardiac insufficiency, and hemodialysis patients. In healthy humans, one study found that carnitine increased endurance, an effect that was potentiated further by caffeine. Some animal studies have also found performance increases from carnitine supplementation. ALA may synergize with ALCAR and further increase exercise performance in two ways. First, it may increase glucose transport to muscle, particularly because exercise is associated with a high degree of oxidative stress. Secondly, ALA and ALCAR may synergize to increase fatty acid utilization and cellular energy production.
A second benefit of ALCAR is fat loss. Studies in animals have found it to decrease fat mass and/or increase lean mass, as well as blunt the age-related increase in fat cell size. In a study in humans, 700 mg carnitine and 900 mg choline caused a significant decrease in body fat. Once again, ALA may synergize by improving mitochondrial function and fatty acid oxidation, as well as having a positive nutrient partitioning effect when used around exercise.
In the area of anti-aging research, Dr. Bruce Ames has had very promising results with this combination of nutrients. Mitochondrial damage is a significant factor in the aging process, and ALCAR greatly improves mitochondrial function when given to old rats. Along with this comes improved short term memory and cognitive function, an effect that has also been observed when elderly humans are given ALCAR. However, Dr. Ames also found that when rodents were given high (but not low) doses of ALCAR, hepatic antioxidant status was lowered. ALA prevented this, and also caused an even further improvement in mitochondrial function. Ames concluded, "Supplementing the diet of old rats with ALCAR and LA significantly improves many of the most frequently encountered age-related changes in mammals – namely loss of energy metabolism, increased oxidative stress, decreased physical activity, and impaired cognitive function."
Clearly, this blend of powerful nutrients has a variety of uses. In addition to those covered here, they may improve cardiovascular health, improve hearing and visual function, relieve depression, and have many other benefits. Some other supplements, such as choline and antioxidant vitamins, may provide added benefit.